2002”N@‰¢•¶
Dobson-Stone C, Danek A, Rampoldi L, Hardie RJ, Chalmers RM, Wood NW,Bohlega S, Dotti MT, Federico A, Shizuka M, Tanaka M, Watanabe M, Ikeda Y, Brin M, Goldfarb LV, Karp BI, Mohiddin S, Fananapazir L, Storch A, Fryer AE, Maddison P, Sibon I, Trevisol-Bittencourt PC, Singer C, Caballero IR, Aasly JO, Schmierer K, Dengler R, Hiersemenzel L-P, Zeviani M, Meiner V, Lossos A, Johnson S, Mercado FC, Sorrentino G, Dupre N, Rouleau GA, Volkmann J, Arpa J, Lees A, Geraud G, Chouinard S, Nemeth A and Monaco AP (2002) Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis. Eur J Hum Genet 10:773-781
Fujita Y, Okamoto K, Sakurai A, Kusaka H, Aizawa H, Mihara B and Gonatas NK (2002)The Golgi apparatus is fragmented in spinal cord motor neurons of amyotrophic lateral sclerosis with basophilic inclusions. Acta Neuropathol 103:243-247
Nagashima K, Torii S, Yi Z, Igaraashi M, Okamoto K, Takeuchi T and Izumi
T (2002) Melanophilin directly links Rab27a and myosisn Va through its
distinct coiled regions. FEBS Lett 517:233-238
Okamoto K, Tanaka M and Kondo S (2002) Treatment of vascular dementia.Ann NY Acad Sci 977: 507-512
Prat MI, Adamo AM, Gonzalez SA, Affranchino JL, Ikeda M, Matsubara E, Shoji M, Smith MA, Castano EM and Morelli L (2002) Presenilin 1 overexpressions in Chinese hamster ovary (CHO) cells decreases the phosphorylation of retinoblastoma protein: relevance for neurodegeneration. Neurosci Lett 326:9-12
Rozmahel R, Huang J, Chen F, Liang Y, Nguyen V, Ikeda M, Levesque G, Yu G, Nishimura M, Mathews P, Schmidt SD, Mercken M, Bergeron C, Westaway D and St George-Hyslop P (2002) Normal brain development in PS1 hypomorphic mice with markedly reduced gamma-secretase cleavage of betaAPP Neurobiol Aging 23:187-94
Sakurai A, Okamoto K, Yaguchi M, Fujita Y, Mizuno Y, Nakazato Y and Gonatas NK (2002) Pathology of the inferior olivary nucleus in patients with multiple system atrophy. Acta Neuropathol 103:550-554
Sasaki A, Shoji M, Harigaya Y, Kawarabayashi T, Ikeda M, Naito M, Matsubara E, Abe K and Nakazato Y (2002) Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neuritis. Virchows Arch 441:358-367
Shizuka-Ikeda M, Matsubara E, Ikeda M, Kanai M, Tomidokoro Y, Ikeda Y, Watanabe M, Kawarabayashi T, Harigaya Y, Okamoto K, Maruyama Km Castano EM, George-Hyslop P St and Shoji M (2002) Generation of amyloid ƒÀ protein from a presenilin-1 and ƒÀAPP complex. Biochem Biophys Res Comm 292:571-578
Shoji M, Matsubara E, Murakami T, Manabe Y, Abe K, Kanai M, Ikeda M, Tomidokoro Y, Shizuka M, Watanabe M, Amari M, Ishiguro K, Kawarabayashi T, Harigaya Y, Okamoto K, Nishimura T, Nakamura Y, Takeda M, Urakami K, Adachi Y, Nakashima K, Arai H, Sasaki H, Kanemaru K, Yamanouchi H, Yoshida Y, Ichise K, Tanaka K, Hamamoto M, Yamamoto H, Matsubayashi T, Yoshida H, Toji H, Nakamura S and Hirai S (2002) Cerebrospinal fluid tau in dementia disorders: a large scale multicenter study by a Japanese study group. Neurobiol Aging 23:363-370
Tanaka M, Okamoto K and Hirai S (2002) Cerebral blood flow and oxygen metabolism in vascular dementia evaluated by positron emission tomography: importance of frontal lobe hypoperfusion and hypometabolism. Ann NY Acad Sci 977:135-140
Uesugi M, Okamoto K, Tanaka M and Gonatas NK (2002) Masses of phosphorylated neurofilaments are associated with abnormal Golgi apparatus of anterior horn neurons of ƒÀ, ƒÀ'-iminodipropionitrile-intoxicated rats. Neuropathology 22(2):61-65
Yoshida T, Tanaka M, Suzuki Y, Sohmia M and Okamoto K (2002) Antioxidant properties of cabergoline: inhibition of brain autoaxidation and spuperoxide anion production of microglial cells in rats. Neurosci Lett 330(1):1-4
Yoshida T, Tanaka M and Okamoto K (2002) Immunoglobulin G induces microglial superoxide production. Neurol Res 24(4):361-364