1999年　欧文

Donoviel DB, Hadjantonakis AK, Ikeda M, Zheng H, Hyslop PS, Bernstein A (1999) Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev 13: 2801-2810

Kanai M, Shizuka M, Urakami K, Matsubara E, Harigaya Y, Okamoto K and Shoji M (1999) Apolipoprotein E4 accelarates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease. Neurosci Lett 267:65-68

Fujita Y, Okamoto K, Sakurai A, Amari M, Nakazato Y and Gonatas NK (1999) Fragmentation of the Golgi apparatus of Betz cells in patients with amyotrophic lateral sclerosis. J Neuro Sci 163:81-85

Levesque G, Yu G, Nishimura M, Zhang DM, Levesque L, Yu H, Xu D, Liang Y, Rogaeva E, Ikeda M, Duthie M, Murgolo N, Wang L, VanderVere P, Bayne ML, Strader CD, Rommens JM, Fraser PE and St George-Hyslop P (1999) Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin. J Neurochem 72:999-1008

Matubara E, Ghiso J, Fragione B, Amari M, Tomidokoro Y, Ikeda Y, Harigaya Y, Okamoto K and Shoji M (1999) Lipoprotein-free amyloidgenic peptides in plasma are elevated in patients wirh sporadic Alzheimer's disease and Down's syndrome. Ann Neurol 45:537-541

Mizushima K, Watanabe M, Kondo I, Okamoto K, SHizuka M, Abe K, Aoki M and Shoji M (1999) Analysis of spinocerebellar ataxia type 2 gene and haplotype analysis:(CCG)1-2 polymorphism and contribution to founder effect. J Med Gen 36:112-114

Shizuka M, Ikeda Y, Watanabe M, Okamoto K, Shoji M, Ikegami T and Hayakawa K (1999) A novel mutation of the myelin P(0) gene segregrating Charcot-Marie-Tooth disease type 1B manifesting as trigeminal nerve thickening. J Neurol Neurosurg Psychiatry 67:250-251

Tanaka M, Yoshida T, Okamoto K and Hirai S (1999) Dopamine and DOPA cause release of iron from ferritin and lipid peroxidation of liposomes. NeuroReprt 10:1883-1887

Tomidokoro Y, Ishiguro K, Igeta Y, Matsubara E, Kanai M, Shizuka M, Kawarabayashi T, Harigaya Y, Kawakatsu S, Ii K, Ikeda M, St George-Hyslop PH, Hirai S, Okamoto K and Shoji M (1999) Carboxyl-terminal fragments of presenilin-1 are closely related to cytoskeletal abnormalities in Alzheimer's brains. Biochem Biophys Res Commun 24;256(3):512-518

Yoshida T, Tanaka M, Sotomatsu A and Okamoto K (1999) Effect of methypredonisolone-pulse therapy on superoxide production of neutrophils. Neurol Res 21:509-512